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  • Title: New steroids and sesquiterpene from Turraea pubescens.
    Author: Yuan CM, Tang GH, Wang XY, Zhang Y, Cao MM, Li XH, Li Y, Li SL, Di YT, He HP, Hao XJ, Hua HM.
    Journal: Fitoterapia; 2013 Oct; 90():119-25. PubMed ID: 23856090.
    Abstract:
    Four new compounds, including three new steroids (1-3) and one new sesquiterpene (6), and two new natural products (4-5), as well as three known steroids (7-9) were isolated from the twigs of Turraea pubescens. Compounds 3-5 are C₂₂ steroids isolated from the Meliaceae family for the first time. Their structures were elucidated by extensive NMR and MS analyses. Compound 1 exhibited inhibitory activity against lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264.7 cells with an IC₅₀ value of 11.5 μM.
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