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  • Title: [An experimental study of the cardio- and hemodynamic effects of the carboxyl ionophore monensin].
    Author: Gurbanov KG, Kovalev GV, Paperno AA.
    Journal: Farmakol Toksikol; 1990; 53(3):17-9. PubMed ID: 2387374.
    Abstract:
    The effect of ionophore monensin on the main parameters of cardio- and hemodynamics was studied in the experiments on anesthetized cats. Monensin (0.075-0.375 mg/kg) administered intravenously in the increasing doses was shown to produce the dose-dependent elevation of arterial blood pressure, the increase of myocardial contractility and the total peripheral resistance. A single administration of monensin (0.375 mg/kg) was found to exert the two-phase action on the parameters of cardio- and hemodynamics.
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