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  • Title: Rheumatoid arthritis. Triple therapy or etanercept after methotrexate failure in RA?
    Author: van Vollenhoven RF, Chatzidionysiou K.
    Journal: Nat Rev Rheumatol; 2013 Sep; 9(9):510-2. PubMed ID: 23897440.
    Abstract:
    Since the 1990s, patients with rheumatoid arthritis have been treated with at least one DMARD. Methotrexate, which is usually the first-line treatment, elicits good or even excellent clinical results in 20–30% of patients—but in most patients it does not. Thus, an important question is what to do after methotrexate failure.
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