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  • Title: [A case of right renal pelvic and ureter cancer with hepatic metastasis showing complete response by M-VAC].
    Author: Sumiyoshi Y, Akiyama K, Yano M.
    Journal: Gan To Kagaku Ryoho; 1990 Aug; 17(8 Pt 1):1521-3. PubMed ID: 2389946.
    Abstract:
    A 69-year-old man was admitted for further examination of right hydronephrosis in November 1988. Radiologically, excretory urography showed right non-functional kidney and antegrade pyelography revealed filling defect of right renal pelvis and ureter. Cytology findings of right renal urine indicated transitional cell carcinoma. Computed tomography revealed multiple mass of liver. The patient was administered M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) combination chemotherapy. After the 4 courses of treatment, the mass of the primary lesion and hepatic metastasis disappeared and he achieved complete remission. The side effects noted were mild myelosuppression, alopecia and gastrointestinal symptoms such as nausea and vomiting.
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