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  • Title: Rhodamine cyclic hydrazide as a fluorescent probe for the detection of hydroxyl radicals.
    Author: Kim M, Ko SK, Kim H, Shin I, Tae J.
    Journal: Chem Commun (Camb); 2013 Sep 18; 49(72):7959-61. PubMed ID: 23903522.
    Abstract:
    A new rhodamine fluorescent probe for monitoring ˙OH has been developed based on the oxidative C-H abstraction reaction of rhodamine cyclic hydrazide. The probe exhibits excellent selectivity for ˙OH with virtually no interference by other ROS/RNS species. Fluorescent imaging of A549 and RAW264.7 cells is also successfully demonstrated to detect intracellular ˙OH in live cells.
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