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  • Title: Rapid response to budesonide (Pulmicort) inhaled via the Nebuhaler in asthmatic children.
    Author: McCarthy TP.
    Journal: Br J Clin Pract; 1990 May; 44(5):180-2. PubMed ID: 2390441.
    Abstract:
    Acute reversible airways obstruction in children, especially those aged under one year, who may respond poorly to inhaled beta 2-stimulants, is difficult to treat in general practice. In an open study, 48 episodes in 29 children, half aged under one year, were treated with budesonide (Pulmicort) 0.1-2.09 mg used to charge a Nebuhaler fitted with a facemask. In 45 instances, clinical improvement was observed, and with doses of 0.8 mg and above, this usually occurred within 10 minutes. This study suggests that budesonide via a suitable delivery system can evoke rapid improvement in reversible airways obstruction in young children.
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