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  • Title: Parental permissions: H19 and keeping the stem cell progeny under control.
    Author: Goodell MA.
    Journal: Cell Stem Cell; 2013 Aug 01; 13(2):137-8. PubMed ID: 23910078.
    Abstract:
    H19 is shown by Venkatraman et al. (2013), using maternal-allele-specific deletion of the differentially methylated region, to maintain hematopoietic stem cell repopulating ability through a miR-675-Igf1r signaling circuit. This work establishes function in somatic stem cells for another member of a putative imprinted gene network that may influence organismal growth.
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