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  • Title: A case of late-onset systemic lupus erythematosus with severe anemia.
    Author: Matsumoto M, Kaieda S, Honda S, Ida H, Hoshino T, Fukuda T.
    Journal: Kurume Med J; 2013; 60(1):25-8. PubMed ID: 23925156.
    Abstract:
    A 59-year-old woman was referred to our hospital because of severe anemia and leucopenia. Although she developed mild arthralgia without the typical symptoms of systemic lupus erythematosus (SLE), positivity for anti-Sm antibodies led us to a diagnosis of late-onset SLE. Autoimmune hemolytic anemia (AIHA) and suppression of reticulocyte production were considered to have been involved in the etiology of severe anemia. Administration of oral prednisolone (PSL) resulted in a marked improvement of the hematological abnormalities. As late-onset SLE is rare and patients tend to show the typical symptoms less frequently, close attention should be focused on latent symptoms and immunological findings.
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