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  • Title: Insights into ancient leprosy and tuberculosis using metagenomics.
    Author: Donoghue HD.
    Journal: Trends Microbiol; 2013 Sep; 21(9):448-50. PubMed ID: 23932433.
    Abstract:
    Leprosy and tuberculosis were widespread in the past and remain significant diseases today. Comparison of ancient and modern genomes of Mycobacterium leprae and Mycobacterium tuberculosis gives insight into their evolution and a calibration of the timescale for observed changes. Recently, whole genome sequencing has revealed genotypes and mixed-strain infections.
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