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  • Title: Clubbing in hypersensitivity pneumonitis. Its prevalence and possible prognostic role.
    Author: Sansores R, Salas J, Chapela R, Barquin N, Selman M.
    Journal: Arch Intern Med; 1990 Sep; 150(9):1849-51. PubMed ID: 2393316.
    Abstract:
    To know the prevalence and prognostic significance of finger clubbing in hypersensitivity pneumonitis induced by avian antigen, this physical sign was evaluated in 82 patients who were followed up from 1 to 5 years (mean, 2.6 years). According to clinical, roentgenographic, and functional criteria, the patients were classified in one of three stages at admission as well as at least 1 year later. Digital clubbing was retrospectively recorded as present or absent by physical examination. Our results showed that 44 patients (51%) included in this study presented clubbing at the time of diagnosis. Sixteen of these patients presented with worsening of their lung disease, whereas only 5 of the 38 patients without clubbing incurred a worsening of their condition. This finding suggests that digital clubbing is frequent in pigeon breeder's disease and may help to predict clinical deterioration.
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