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  • Title: [The action of prostaglandin E2-induced pains on the metabolic and clotting systems of mother and child during birth (author's transl)].
    Author: Neumayer E, Stark KH, Klausch B, Junge WD, Töwe J.
    Journal: Z Geburtshilfe Perinatol; 1975 Apr; 179(2):125-31. PubMed ID: 239495.
    Abstract:
    11 pregnancies at term were terminated by dilatation of the uterine cervix, low amniotomy, and by intravenous administration of PGE2. The average infusion time was 4 hours 20 minutes, and the average total dose of PGE2 amounted to 0.2 mg. Parameters of acid-base changes, carbohydrate and energic state changes, gas metabolism, and changes in coagulation and fibrinolysis in mother and in fetus were analysed during labor and after birth. Labor activity and fetal cardiac action were monitored cardiotocographically. Checked against 50 uncomplicated spontaneous deliveries, we have found no disadvantageous changes in the parameters investigated.
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