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  • Title: A squaraine and Hg(2+)-based colorimetric and "turn on" fluorescent probe for cysteine.
    Author: Lin Q, Huang Y, Fan J, Wang R, Fu N.
    Journal: Talanta; 2013 Sep 30; 114():66-72. PubMed ID: 23953443.
    Abstract:
    A novel squaraine derivative (SQ-1) was synthesized and characterized for the determination of cysteine. Binding with Hg(2+) as a fluorescent quencher to SQ-1 leads to absorption and emission turn-off. More significantly, the SQ-1-Hg(2+) complex exhibits a dual-channel chromofluorogenic responses to biologically important cysteine with a high sensitivity and selectivity over other natural amino acids, along with a low detection limit of 36.7 nM.
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