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  • Title: Bone pain as the presenting manifestation of secondary syphilis.
    Author: Middleton S, Rowntree C, Rudge S.
    Journal: Ann Rheum Dis; 1990 Aug; 49(8):641-2. PubMed ID: 2396873.
    Abstract:
    A 31 year old fireman presented with acute pain and tenderness in both shins and forearms. Radiographs were normal but bone scintigraphy showed widespread increased isotope uptake. Serology was consistent with a diagnosis of secondary syphilis, and the patient's symptoms resolved completely six weeks after a course of penicillin.
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