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  • Title: [The morphological characteristics of psoriatic nephropathy].
    Author: Varshavskiĭ VA, Panasiuk NN, Antonov MV, Fal'kovskaia OG.
    Journal: Arkh Patol; 1990; 52(5):32-6. PubMed ID: 2396915.
    Abstract:
    Three variants of psoriatic nephropathy are distinguished on the basis of light microscopical and immunohistochemical study of 23 cases/20 kidney biopsies and 3 autopsy cases/: glomerulonephritis, amyloidosis and minimal kidney alterations. Chronic glomerulonephritis is mainly of a mesangioproliferative type with fixation of IgA and C3 on the mesangium and basal membranes of glomerular capillaries. Psoriatic amyloidosis has morphologically, all the features of acquired amyloidosis/AA-amyloidosis/. Thus psoriatic nephropathy is a reflection of a disturbed homeostasis.
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