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  • Title: Sequencing therapy in metastatic renal cell cancer.
    Author: Escudier B, Gore M.
    Journal: Semin Oncol; 2013 Aug; 40(4):465-71. PubMed ID: 23972710.
    Abstract:
    The sequencing of targeted therapy is well established in metastatic renal cancer. Switching between different vascular endothelial growth factor (VEGF)-targeted therapies or VEGF-targeted therapies and mammalian target of rapamycin (mTOR) inhibitors are both of proven benefit. The optimal sequence remains unclear. Unfortunately, there is a lack of biomarkers to drive decision making. In this article we review the current data and describe the treatment options for patients.
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