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  • Title: Cytogenetic study of a case of childhood erythroleukemia.
    Author: Duarte MH, Tone LG, Soares LR, dos Santos SA.
    Journal: Cancer Genet Cytogenet; 1990 Oct 01; 49(1):25-30. PubMed ID: 2397470.
    Abstract:
    We report a case of childhood erythroleukemia diagnosed by French-American-British Cooperative group (FAB) and by cytogenetic analysis of bone marrow cells. The following major chromosome anomalies were detected: hyperdiploidy with a modal number of 49, three markers consisting of translocations between chromosomes 3, 9, 20, and 15, deletion of the long arm of chromosome 16 (q22----qter), and karyotype instability. These changes were compared with others reported in the literature and discussed in terms of their importance for diagnostic confirmation.
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