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  • Title: Gastric secretion during anaesthesia and its inhibition by metiamide and other drugs.
    Author: Schachter M, Karpinski E, Haines V.
    Journal: Experientia; 1975 Aug 15; 31(8):964-5. PubMed ID: 239857.
    Abstract:
    The histamine H2-receptor antagonist, metiamide, inhibits the acid gastric secretion produced by chloralose-urethane anaesthesia in dogs carrying gastric cannulae chronically. This secretion is also prevented by atropine and hexamethonium. "Spontaneous" gastric secretion of vagal origin in conscious dogs is also blocked by metiamide.
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