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  • Title: Complete agenesis of major salivary glands.
    Author: Berta E, Bettega G, Jouk PS, Billy G, Nugues F, Morand B.
    Journal: Int J Pediatr Otorhinolaryngol; 2013 Oct; 77(10):1782-5. PubMed ID: 23993206.
    Abstract:
    A 4 year-old female patient was treated for persistent right-sided dacryocystitis and xerostomia. MRI was performed to screen for a dry syndrome; which resulted in the diagnosis of agenesis of the parotid and submandibular glands as well as lacrimal duct malformation. An MRI of each parent was normal. The mother's history revealed 4 days of pyrexia during the 8th week of amenorrhea. This was an isolated case, with no family history, characterized by a febrile episode during pregnancy at the period of main salivary gland genesis. Epigenetic mechanisms could be implicated.
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