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  • Title: Response of the epididymis, ductus deferens & accessory glands of the castrated prepubertal rhesus monkey to exogenous administration of testosterone or 5alpha-dihydrotestosterone.
    Author: Arora-Dinakar R, Dinakar N, Prasad MR.
    Journal: Indian J Exp Biol; 1977 Oct; 15(10):829-34. PubMed ID: 23997.
    Abstract:
    The response of the epididymis, ductus deferens, and accessory glands of the castrated prepubertal rhesus monkey to exogenous administration of testosterone or 5alpha-dihydrotestosterone (DHT) was investigated. 200 or 800 mcg of either steroid/day were administered for 60 days beginning on the day after castration. Castration caused a marked regression of the weight of and secretory function of the reproductive organs; testosterone/DHT stimulated their growth and secretory activity which were maintained at the level of the controls. The weight of the caput epididymides however, was unaffected by testosterone but was stimulated by DHT. DHT caused a greater stimulation of the growth and secretory activity of the reproductive organs than testosterone and also caused a hyperstimulation of secretion by the seminal vesicles. The data, analyzed statistically, show that the accessory organs of the prepubertal rhesus monkey are affected by castration and vary in their response to stimulation by exogenous androgens.
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