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  • Title: Urinary phenylacetic acid in panic disorder with and without depression.
    Author: Sabelli HC, Javaid JI, Fawcett J, Kravitz HM, Wynn P.
    Journal: Acta Psychiatr Scand; 1990 Jul; 82(1):14-6. PubMed ID: 2399814.
    Abstract:
    Phenylacetic acid (PAA) excretion was measured in 39 patients who met criteria for panic disorder; 9 of these also had major depression, and 30 did not. Patients with panic and depression excreted 66 +/- 23 mg/day of PAA, an amount significantly lower than in normal controls; patients with panic disorder but without depression excreted 104 +/- 23 mg/day of PAA (not significantly lower than controls). The results support previous studies indicating that PAA excretion is a marker for depressive disorder.
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