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  • Title: [Secondary osteoporosis or secondary contributors to bone loss in fracture. Vitamin D deficiency and fracture].
    Author: Watanabe R, Okazaki R.
    Journal: Clin Calcium; 2013 Sep; 23(9):1313-9. PubMed ID: 23999368.
    Abstract:
    Vitamin D plays an important role in maintaining bone and calcium metabolism. Vitamin D deficiency causes not only low bone mineral density via secondary hyperparathyroidism, but also impairment of bone mineralization. Vitamin D deficiency also increases the risk of fall. Thus, vitamin D deficiency results in increased fracture risk. Serum 25 (OH) D level reflects Vitamin D store and more than 30 ng/mL is recommended for bone health, but the measurement of serum 25 (OH) D is not reimbursed by Japanese health insurance system. Vitamin D supplementation to vitamin D deficient osteoporotics reduces the fracture incidence by both increasing bone mineral density and reducing falls. Evaluation of vitamin D status and its adequate supplementation are prerequisite for proper osteoporosis management.
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