These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Caesanines A-D, new cassane diterpenes with unprecedented N bridge from Caesalpinia sappan.
    Author: Zhang J, Abdel-Mageed WM, Liu M, Huang P, He W, Li L, Song F, Dai H, Liu X, Liang J, Zhang L.
    Journal: Org Lett; 2013 Sep 20; 15(18):4726-9. PubMed ID: 24004304.
    Abstract:
    Serial antibacterial furanoditerpenes caesanines A-D (1-4), possessing a cassane-type diterpenoid skeleton with an unusual N bridge between C-19/C-20, were identified from a Chinese herb Caesalpinia sappan Linn. In addition, caesanine D (4) showed the first class of dicassane diterpenoid ethers. Their structures were determined by different spectroscopic methods and ECD calculation. Caesanines A and B exhibited strong activities against MRSA suggesting a promising entry point for the development of anti-infective drugs.
    [Abstract] [Full Text] [Related] [New Search]