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  • Title: Researches on antiinflammatory agents. Studies on some new 3-(pyrazol-5-yl)-1,2,3-benzotriazin-4(3H)-ones and -quinazolin-4(3H)-ones.
    Author: Daidone G, Plescia S, Raffa D, Bajardi ML, Matera M, Caruso A, Leone MG.
    Journal: Farmaco; 1990 Apr; 45(4):391-8. PubMed ID: 2400513.
    Abstract:
    Following our research on analgesic and antiinflammatory active compounds containing the pyrazole nucleus, a number of 3-(pyrazol-5-yl)-1,2,3-benzotriazin-4(3H)-ones and quinazolin-4(3H)-ones was synthetized and tested. The results of tests for analgesic, antiexudative and antioedema activities, as well as for induction of lesion in the gastric mucosa, are reported and discussed.
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