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  • Title: Eudismic analysis of a series of muscarinic ligands carrying a 1,3-oxathiolane nucleus.
    Author: Gualtieri F, Romanelli MN, Teodori E.
    Journal: Chirality; 1990; 2(2):79-84. PubMed ID: 2400641.
    Abstract:
    Eudismic analysis was performed on a set of 14 muscarinic ligands carrying a 1,3-oxathiolane nucleus, in order to obtain information about both the existence of receptor subgroups and of agonist and competitive antagonist interaction sites. The results obtained were compared with those from a study of the enantioselectivity of the pairs of enantiomers. The two approaches do not appear to be completely equivalent and would seem to complement each other usefully.
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