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  • Title: Partially reversible cardiomyopathy after renal transplant associated with anti-troponin I antibodies.
    Author: Nunes JP, do Sameiro Faria M, Sampaio S, Quintas J, Katus HA, Kaya Z.
    Journal: Cardiology; 2013; 126(3):173-4. PubMed ID: 24009043.
    Abstract:
    Cardiomyopathy associated with dialysis has been shown to be reversible in some cases. A 58-year-old female patient with polycystic renal disease and end-stage renal disease had a renal transplant after 9 years on hemodialysis. Dilated cardiomyopathy with depressed left ventricular ejection fraction markedly improved after transplantation, with normalization of the ejection fraction. High titers for anti-troponin I antibodies were measured: IgG 1:640, IgM 1:80. In our case, the presence of anticardiac (anti-troponin I) antibodies may suggest that the syndrome of reversible cardiomyopathy seen after renal transplantation is associated with immunosuppression therapy acting on immunological mechanisms previously at play.
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