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  • Title: Axotomy decreases conduction velocity of unmyelinated sensory fibres.
    Author: Gallego R, Adrover E.
    Journal: Brain Res; 1990 Jul 23; 523(2):298-300. PubMed ID: 2400914.
    Abstract:
    We have examined the effect of axotomy on the conduction velocity of unmyelinated sensory fibres in the vagus nerve of the rabbit. In an in vitro preparation of the nodose ganglion, conduction velocity was calculated for each cell from the latency of the intracellularly recorded action potential evoked by vagus nerve stimulation. The average velocity of sensory fibres conducting at less than 1.1 m/s, was 0.53 m/s in 287 control cells and 0.45 m/s in 269 neurones recorded 10 days after cutting the vagus nerve. Therefore, peripheral axotomy decreases conduction velocity in mammalian unmyelinated sensory axons.
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