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  • Title: "Blueberry muffin" rash and large right thigh mass: a unique presentation of Langerhans cell histiocytosis.
    Author: Lau EG, Stepenaskie S, Moran R, Quinn R, Matthew P, Smidt AC.
    Journal: Dermatol Online J; 2013 Jun 15; 19(6):18568. PubMed ID: 24011317.
    Abstract:
    Langerhans cell histiocytosis (LCH) is a clonal proliferation of bone marrow derived antigen-presenting cells that can involve a spectrum of cutaneous findings, with or without internal organ involvement. Neonatal LCH almost always presents with skin findings, usually petechial papules and/or erosions in a seborrheic distribution, with or without extracutaneous involvement. Previously described as varying entities, LCH is now considered a single disease process demonstrating a spectrum of clinical findings. We report a unique case of neonatal LCH presenting with a "blueberry muffin" rash in conjunction with a large soft tissue tumor.
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