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  • Title: Lateral flow biosensors for the detection of nucleic acid.
    Author: Zeng L, Lie P, Fang Z, Xiao Z.
    Journal: Methods Mol Biol; 2013; 1039():161-7. PubMed ID: 24026695.
    Abstract:
    The detection of nucleic acid is of central importance for the diagnosis of genetic diseases, infectious agents, and biowarfare agents. Traditional strategies and technologies for nucleic acid detection are time-consuming and labor-intensive. Recently, isothermal strand-displacement reaction-based lateral flow biosensors have attracted a great deal of research interest because they are sensitive, simple, fast, and easy to use. Here, we describe a lateral flow biosensor based on isothermal strand-displacement polymerase reaction and gold nanoparticles for the visual detection of nucleic acid.
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