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  • Title: [Stress-resistance and the condition of surfactant system and water balance in the lung of suspended rats].
    Author: Bryndina IG, Vasilieva NN, Baranov VM.
    Journal: Aviakosm Ekolog Med; 2013; 47(3):34-7. PubMed ID: 24032163.
    Abstract:
    White male rats with the body mass of 180-220 grams were distributed into the open-field active (presumably stress-resistant) and open-field inactive (presumably stress vulnerable) groups for a 10-day experimental suspension with the purpose to evaluate the surfactant activity in bronchoalveolar lavages, total phospholipids and their fractions, and water balance in the lung. In modeled microgravity, augmented blood filling of the rat's lung increases the alveolar phospholipid content and alters the phospholipid fractional composition in the pulmonary surfactant. Ten-day suspension raises pulmonary surfactant activity to a greater extent in stress-resistant animals rather than in their stress vulnerable peers.
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