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  • Title: Sepsis, resuscitated hemorrhagic shock and "shock lung:" An experimental correlation.
    Author: Esrig BC, Fulton RL.
    Journal: Ann Surg; 1975 Sep; 182(3):218-27. PubMed ID: 240329.
    Abstract:
    Dogs were submitted to hermorrhagic shock, resuscitated shock and resuscitated shock plus a pulmonary bacterial insult. Pulmonary familure was absent in dogs submitted only to shock or to shock and its resuscitation. The addition of usually sub-lethal amounts of micro-organisms to the shock-resuscitated lung caused rapid death from pulmonary failure. Pulmonary failure was demonstrated by increased lung weight, hypoxemia, decreased compliance and a hemorrhagic destruction of lung tissue. These findings strongly support recent concepts of an infective genesis of "shock lung" in man.
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