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  • Title: Cryptococcal meningitis presenting as sinusitis in a renal transplant recipient.
    Author: Iyer SP, Movva K, Wiebel M, Chandrasekar P, Alangaden G, Carron M, Tranchida P, Revankar SG.
    Journal: Transpl Infect Dis; 2013 Oct; 15(5):E187-90. PubMed ID: 24034280.
    Abstract:
    Cryptococcal meningitis is a relatively common invasive fungal infection in immunocompromised patients, especially in solid organ transplant recipients. Clinical presentation typically includes fever, headache, photophobia, neck stiffness, and/or altered mental status. Unusual presentations may delay diagnosis. Therapy is challenging in renal transplant patients because of the nephrotoxicity associated with amphotericin B, the recommended treatment. We present a case of cryptococcal meningitis in a renal transplant recipient presenting as acute sinusitis with successful treatment using fluconazole as primary therapy.
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