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  • Title: [Anti-Hu antibody syndrome: diagnostic and therapeutic difficulties].
    Author: Leroy T, Porte H, Rousselot C, Taieb S, Outteryck O, Dansin É.
    Journal: Rev Mal Respir; 2013 Sep; 30(7):563-6. PubMed ID: 24034461.
    Abstract:
    INTRODUCTION: Anti-Hu antibody syndrome is a paraneoplastic syndrome usually associated with small cell lung carcinoma which induces various symptoms, particularly neurological ones. CASE REPORT: We describe the case of a 49-year old woman with a small cell lung carcinoma who initially experiences a spontaneous regression but then developed neurological symptoms associated with severe autonomic dysfunction manifesting as chronic intestinal pseudo-obstruction and leading finally to hemodynamic failure. CONCLUSION: Anti-Hu antibody syndrome remains a rare entity. Its diagnosis must be considered in the face of neurologic symptoms associated with small cell lung cancer.
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