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  • Title: [Extraneural soft tissue perineurioma of the nose].
    Author: Zaouak A, Benmously R, Belhadj Salah M, Koubaa W, Debbiche A, Mokhtar I.
    Journal: Ann Dermatol Venereol; 2013; 140(8-9):540-3. PubMed ID: 24034640.
    Abstract:
    BACKGROUND: Perineuriomas are tumours derived from the perineurial cells of the neural sheath. Soft tissue perineuriomas are rare. Herein, we report a case of perineurioma localized to the nose. CASE REPORT: A 24-year-old adult presented with a cutaneous nodule 1cm in diameter localized on the nose. Histologically, the tumour corresponded to a well-circumscribed fusocellular dermal proliferation organized in a storiform pattern. After surgical removal, the lesion did not recur. COMMENTS: Extraneural soft tissue perineurioma is usually a benign nerve sheath tumour composed mainly of perineurial cells. Our case occurred in a 24-year-old Caucasian adult. The tumour generally presents as a unique cutaneous nodule corresponding histologically to a well-delineated dermal fusocellular proliferation organized in a storiform pattern that stains positive for EMA and negative for S100. The tumour is usually localized to the trunk and extremities. Location on the nose as in our patient has been rarely reported. Surgical removal of the tumour is the treatment of choice.
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