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  • Title: A chronic subdural hematoma in a patient receiving combination therapy with pegylated interferon alfa-2b and ribavirin for chronic hepatitis C.
    Author: Goto T, Ohshima S, Miura K, Shibuya T, Sato W, Dohmen T, Kamada K, Kanata R, Sakai T, Chiba M, Sugimoto Y, Minami S, Ohnishi H.
    Journal: Intern Med; 2013; 52(18):2057-60. PubMed ID: 24042512.
    Abstract:
    A 70-year-old man who suffered from chronic hepatitis C was infected with HCV genotype 1 and exhibited a high viral load. He had hypertension and had consumed the equivalent of 50 g of ethanol per day. He was treated with pegylated interferon and ribavirin. After 51 weeks, he developed an unsteady gait while walking and demonstrated Barre's sign on the right foot and a headache. Contrast computed tomography showed a subdural hematoma with a mass effect. The patient was treated with drainage and aspiration surgery via a burr hole. Following the drainage procedure, there were no neurological sequelae. Treatment with pegylated interferon and ribavirin was discontinued. Fortunately, a sustained virological response was achieved.
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