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  • Title: From symmetric to asymmetric design of bio-inspired smart single nanochannels.
    Author: Zhang H, Tian Y, Jiang L.
    Journal: Chem Commun (Camb); 2013 Oct 03; 49(86):10048-63. PubMed ID: 24048227.
    Abstract:
    Biological nanochannels, such as ion channels and ion pumps, existing in cell membranes and intelligently controlling ions through the cell membrane serve as a big source of bio-inspiration for the scientists to build artificial functional nanochannels. In this Feature Article, a general strategy for the design and synthesis of bio-inspired smart single nanochannels is presented, and put into context with recent progress in constructing symmetric and asymmetric smart single polymer nanochannels with single/double artificial gates which can respond to single/multiple external stimuli, e.g., pH, ions, temperature, light, and molecules. This article is intended to utilize specific stimulus-dependent ionic transport properties inside the single nanochannel as an example to demonstrate the feasibility of the design strategy, and provide an overview of this fascinating research field.
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