These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Inverse relationship between vitamin D status and insulin resistance and the risk of impaired fasting glucose in Korean children and adolescents: the Korean National Health and Nutrition Examination Survey (KNHANES) 2009-2010.
    Author: Chung SJ, Lee YA, Hong H, Kang MJ, Kwon HJ, Shin CH, Yang SW.
    Journal: Public Health Nutr; 2014 Apr; 17(4):795-802. PubMed ID: 24050711.
    Abstract:
    OBJECTIVE: To investigate whether low vitamin D status was related to insulin resistance (IR) or impaired fasting glucose (IFG) in Korean adolescents, after adjusting for total body fat mass (FM). DESIGN: A cross-sectional study. SETTING: Korea National Health and Nutrition Examination Survey (KNAHNES) 2009-2010. SUBJECTS: In total, 1466 participants (769 males) aged 10-19 years were assessed for serum 25-hydroxyvitamin D (25(OH)D) levels, for FM by whole-body dual-energy X-ray absorptiometry and for IR by homeostasis model assessment (HOMA-IR) after an 8 h fast. RESULTS: Age-, sex-, season- and physical-activity-adjusted regression models showed that serum 25(OH)D levels were significantly related to markers of adiposity (P = 0.016 for FM (g), P = 0.023 for FM (%) and P = 0.035 for fat mass index). When the participants were stratified into three 25(OH)D categories (<37.5 nmol/l (n 553), 37.5 to < 50 nmol/l (n 543) and ≥ 50 nmol/l (n 370)), significantly decreasing trends were observed for fasting insulin (all P < 0.001), HOMA-IR (all P < 0.001) and the odds ratios for IFG (all P for trend < 0.05) from the lowest to the highest 25(OH)D category, after adjustments for age, sex, physical activity and all markers of adiposity. In the multivariate logistic regression analysis, the likelihood of participants in the lowest serum 25(OH)D category having IFG was 2.96-3.15 compared with those in the highest 25(OH)D category (all P < 0.05). CONCLUSIONS: There was a significant inverse relationship between vitamin D status and IR and the risk of IFG, independent of adiposity, in Korean adolescents.
    [Abstract] [Full Text] [Related] [New Search]