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  • Title: End-expiratory pressure best approximates intrinsic lower esophageal sphincter pressure. Report of a patient with Cheyne-Stokes respiration.
    Author: Marshall JB, Berger WL.
    Journal: Dig Dis Sci; 1990 Feb; 35(2):267-70. PubMed ID: 2406113.
    Abstract:
    Recent studies have shown that the respiratory oscillation inherent in the station pull-through technique of measuring lower esophageal sphincter (LES) pressure is the result of active diaphragmatic contraction. A recent study in cats suggested that intrinsic LES tone is best reflected by end-expiratory pressure during spontaneous respiration. This finding is confirmed in a patient we report with achalasia and Waldenstrom's macroglobulinemia who had Cheyne-Stokes breathing. LES pressure during periods of central apnea approximated end-expiratory pressure during periods of hyperpnea.
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