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  • Title: Syphilitic uveitis in a Singaporean population.
    Author: Yap SC, Tan YL, Chio MT, Teoh SC.
    Journal: Ocul Immunol Inflamm; 2014 Feb; 22(1):9-14. PubMed ID: 24063580.
    Abstract:
    PURPOSE: To report the presentations of syphilitic uveitides in Singapore. METHODS: Retrospective noncomparative observational case series of 18 eyes from 12 patients with ocular syphilis between 2004 and 2009. RESULTS: Patients were mainly male (91.7%). Median age was 49.5 (24-84) years. Initial visual acuity varied from 6/6 to counting fingers (CF) and was ≥6/12 in 7 eyes (38.8%). Blurring of vision (n = 11, 61.1%) was the most common presenting complaint. Anterior uveitis and panuveitis were both most common (n = 6, 33.3%). Treponemal and nontreponemal serologies were positive in 12 (100.0%) and 10 (83.3%) patients, respectively. Patients were treated systematically with penicillin therapy by infectious disease physicians. CONCLUSIONS: Ocular syphilis is seeing a worldwide resurgence. Although anterior uveitis and panuveitis were most common in this study, there was a large spectrum of ocular manifestations. Syphilitic uveitides can potentially cause severe loss of vision but are effectively treated by an appropriate regimen of penicillin.
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