These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Cytotoxic deoxybenzoins and diphenylethylenes from Arundina graminifolia.
    Author: Hu QF, Zhou B, Ye YQ, Jiang ZY, Huang XZ, Li YK, Du G, Yang GY, Gao XM.
    Journal: J Nat Prod; 2013 Oct 25; 76(10):1854-9. PubMed ID: 24063582.
    Abstract:
    Eight new C-4-alkylated deoxybenzoins (1-8), three new diphenylethylenes (9-11), and five known diphenylethylenes were isolated from Arundina graminifolia. The structures of 1-11 were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 9-11 are the first naturally occurring diphenylethylenes possessing a hydroxyethyl unit. Compounds 1-11 were evaluated for cytotoxicity against five human tumor cell lines. Compounds 4, 5, and 9-11 showed significant cytotoxicity against five cancer cell lines, with IC50 values ranging from 1.8 to 8.7 μM.
    [Abstract] [Full Text] [Related] [New Search]