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  • Title: Juvenile xanthogranuloma: diverse presentations of noncutaneous disease.
    Author: Murphy JT, Soeken T, Megison S, Perez E.
    Journal: J Pediatr Hematol Oncol; 2014 Nov; 36(8):641-5. PubMed ID: 24065046.
    Abstract:
    Juvenile xanthogranulomas (JXGs) are benign cutaneous lesions of childhood that often spontaneously involute. They rarely present as a noncutaneous tumors. However, JXG tumors have been described in numerous noncutaneous anatomic sites, presenting with a variety of symptoms. The severity of symptoms and accurate preoperative diagnosis of JXG should determine operative and nonoperative treatment options of these uncommon, benign, and self-limiting tumors. We report 3 cases of symptomatic, noncutaneous JXG from disparate anatomic sites all treated with aggressive surgical resection.
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