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  • Title: Vein of Galen malformation presenting as persistent pulmonary hypertension of newborn (PPHN).
    Author: Tiwary S, Geethanath RM, Abu-Harb M.
    Journal: BMJ Case Rep; 2013 Sep 26; 2013():. PubMed ID: 24072831.
    Abstract:
    Arteriovenous malformation is a recognised cause of persistent pulmonary hypertension in a newborn (PPHN). Vein of Galen malformation (VOGM) is a rare vascular malformation which can be life-threatening if not diagnosed and treated early. We describe a case of a term baby who presented at day 4 of life with PPHN secondary to VOGM. The neonate underwent two transarterial interventional embolisation procedures on day 9 and then another one due to developing ventricular dilation on day 44. He remains stable since and was doing well at clinical review at 10 weeks and 4 months of age. VOGM usually presents in the neonatal period with high-output cardiac failure. In a baby who presents atypically with pulmonary hypertension, a cranial ultrasound scan should be considered to look for extracardiac shunting in the brain, especially, VOGM.
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