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  • Title: Arsenic exposure affects embryo development of sea urchin, Paracentrotus lividus (Lamarck, 1816).
    Author: Gaion A, Scuderi A, Pellegrini D, Sartori D.
    Journal: Bull Environ Contam Toxicol; 2013 Nov; 91(5):565-70. PubMed ID: 24077651.
    Abstract:
    Toxicity tests were performed with embryos of Paracentrotus lividus to investigate the toxicological effect of two arsenic species: arsenate (As(V)), expected to be more toxic, and dimethyl-arsinate (DMA) expected to be less toxic. Exposures to toxicants were performed at different developmental stages in order to identify the most sensitive phase of embryological development. Statistical analysis revealed a high significance of each factor (Molecule, Concentration and Time of exposure) and their interaction for the dependent variable "Percentage of normal-shaped plutei". In particular, the 8 cell stage was the most sensitive to arsenic; at a concentration of 50 μg L(-1) DMA proved to be more toxic than As(V), resulting in nearly 50 % of normal-shaped plutei against the 74 % recorded for As(V). Starting the administration of arsenic at the morula stage, arsenate proved to be significantly more toxic when compared to DMA.
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