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  • Title: Transapical closure of mitral paravalvular leaks with use of amplatzer vascular plug III.
    Author: Smolka G, Pysz P, Jasinski M, Gocoł R, Domaradzki W, Hudziak D, Deja M, Ochała A, Gasior Z.
    Journal: J Invasive Cardiol; 2013 Oct; 25(10):497-501. PubMed ID: 24088422.
    Abstract:
    INTRODUCTION: Paravalvular leak (PVL) may complicate cardiac valve replacement surgery. Radical treatment is required if a PVL produces heart failure (HF) symptoms or severe hemolysis. Even though transcatheter PVL closure (TPVLC) has become a valid alternative to reoperation, a number of anatomical conditions may prove technically challenging for transvascular access. We intended to verify the utility of transapical access in such settings. METHODS: We report a prospective series of 7 patients with mitral PVLs who underwent transapical TPVLC. The Heart Team made the choice of treatment and Amplatzer Vascular Plug III devices were used off-label as occluders. RESULTS: Transapical TPVLC enabled excellent sealing of mitral PVL in 6 cases. This resulted in HF symptom reduction and decreased NT-proBNP plasma concentration. No procedure-related complications occurred. CONCLUSIONS: Transapical access seems to be an efficient and safe alternative for transvascular approach for mitral TPVLC, but further technical development is still needed.
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