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  • Title: 7S class-restricted hapten-specific paralysis by injection of thymus-independent hapten-carrier conjugate.
    Author: Del Guercio P, Poirier MF, Thobie N.
    Journal: J Immunol; 1975 Nov; 115(5):1239-42. PubMed ID: 240889.
    Abstract:
    The shift from IgM anti-hapten antibody production to IgG anti-hapten antibody production, subsequent to challenge with a T-dependent conjugate, is inhibited in mice by preimmunization with the T-independent DNP-LE conjugate. The results suggest that DNP on levan triggers off 19A T-independent anti-hapten precursors and paralyzes 7S T-dependent anti-hapten precursors.
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