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  • Title: The effects of interferon on murine erythropoiesis.
    Author: Huie ML, Gordon AS, Mirand EA, Leong S, Preti RA, Naughton BA.
    Journal: Life Sci; 1985 Jul 01; 36(26):2459-62. PubMed ID: 2409421.
    Abstract:
    The effects of interferon (IF) on erythropoietin (Ep) action and production were studied in mice. In comparison to control animals, Ep action in exhypoxic, polycythemic mice was significantly decreased (p less than 0.05) following two low dose injections of IF (2.9-3.5 X 10(4) units). In addition, renal Ep production in normal intact mice was also significantly decreased (p less than 0.01) following a single injection of IF (5.4-6.3 X 10(4) units) and hypoxic exposure.
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