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  • Title: [Cell wall antigenic determinants in ribosomal preparations of Streptococcus group A].
    Author: Shikhman AR, Nikolaeva LV, Kondrakova OA, Dzantiev BB, Blinnikova EI.
    Journal: Zh Mikrobiol Epidemiol Immunobiol; 1985 Apr; (4):15-9. PubMed ID: 2409717.
    Abstract:
    As revealed by double immunodiffusion and the competitive immunoenzyme assay, the immunization of animals with ribosomes isolated from group A streptococci leads to the formation of antibodies to M-protein and does not lead to the formation of antibodies to A-polysaccharide and lipoteichoic acid, which is seemingly caused by the presence of M-protein in ribosomes. Antiribosomal serum has permitted the detection of more antigenic determinants in M-protein than commercial antiserum to homologous M-protein. The immunoenzyme assay for the quantitative determination of ribosomes has been developed.
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