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  • Title: Probable histamine liberation with atracurium. A case report.
    Author: Lavery GG, Boyle MM, Mirakhur RK.
    Journal: Br J Anaesth; 1985 Aug; 57(8):811-3. PubMed ID: 2410000.
    Abstract:
    An histaminoid reaction after the administration of thiopentone and atracurium is described. Serial blood sampling showed no evidence of complement activation. Intradermal testing 6 weeks later yielded a positive result with atracurium (1 in 1000), but not with thiopentone. The clinical course of the reaction and the subsequent investigations suggest a direct pharmacological liberation of histamine.
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