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  • Title: [Use of a protein-cellulose complex for inducing intensive antibody formation in mice].
    Author: Korukova AA, Grigor'eva OS, Gurvich AE.
    Journal: Biull Eksp Biol Med; 1985 Jul; 100(7):44-6. PubMed ID: 2410055.
    Abstract:
    The protein-cellulose complex prepared by covalent immobilization of single protein molecules on insoluble cellulose particles was used for priming C57BL/6 and BALB/c mice. The serum antibody content and the number of spleen AFC were assayed after animals' boosting with the soluble protein. Such a complex was shown to have marked advantages over the same protein injected both in complete Freund's adjuvant and in a soluble form, in particular. The immune response of BALB/c mice was more than 10-fold higher than that of C57BL/6 animals.
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