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  • Title: AA amyloidosis in a polyarteritis nodosa patient treated with tocilizumab.
    Author: Hočevar A, Lestan B, Šemrl SS, Lakota K, Kojc N, Potočnik N, Tomšič M.
    Journal: Amyloid; 2013 Dec; 20(4):275-6. PubMed ID: 24106820.
    Abstract:
    Amyloid A (AA) (secondary) amyloidosis represents a severe complication of chronic inflammatory diseases. Since pathogenic mechanisms point to the central role of interleukin 6 (IL-6) in the process of amyloid AA generation, IL-6 blockade seems an attractive therapeutic option. We report a case of a patient with polyarteritis nodosa complicated by AA amyloidosis treated with tocilizumab.
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