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  • Title: False-positive amniotic fluid acetylcholinesterase results: the need for a multifacet approach to the prenatal diagnosis of neural tube defects.
    Author: Lee JE, Ng WG, Falk RE, Alfi O, Lopez L, Platt LD.
    Journal: Obstet Gynecol; 1985 Sep; 66(3 Suppl):22S-24S. PubMed ID: 2410841.
    Abstract:
    Two cases are presented with false-positive amniotic fluid alpha-fetoprotein and acetylcholinesterase results for the prenatal diagnosis of neural tube defects. Stage II ultrasound revealed no lesions of the fetal spine in both cases. The alpha-fetoprotein and acetylcholinesterase results returned to normal on subsequent taps. Both pregnancies resulted in normal outcomes. A protocol is presented for managing pregnancies with abnormal alpha-fetoprotein and acetylcholinesterase results.
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